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Differing Clinical Impact of BRCA1 and BRCA2 Mutations in Serous Ovarian Cancer – Pharmacogenomics. 2012;13(13):1523-1535. 5-year survival for stage III and IV (%): carriers, 38.1; noncarriers, 24.5 Median survival: p = 0.002 5-year survival for stage III and IV: p < 0.001 [46.